Ingabe i-Dialyzer ingasetshenziswa kabusha ekwelashweni kwe-Hemodialysis?
I-Dialyzer, esetshenziswa kakhulu ekwelashweni kwe-dialysis yezinso, isebenzisa isimiso se-membrane engena kancane ukuze ingenise igazi elivela ezigulini ezinenkinga yezinso bese i-dialysate ingena kwi-dialyzer ngesikhathi esifanayo, futhi yenze lokhu kugeleza okubili ngezindlela eziphambene kuzo zombili izinhlangothi ze-dialysis membrane, ngosizo lwe-solute gradient ezinhlangothini zombili, i-osmotic gradient, kanye ne-hydraulic pressure gradient. Le nqubo yokuhlakazeka ingasusa ubuthi namanzi amaningi emzimbeni ngenkathi igcwalisa izinto ezidingekayo zomzimba futhi igcina ibhalansi yama-electrolyte kanye ne-acid-base.
Ama-dialyzer akhiwe kakhulu ngezakhiwo zokusekela kanye nama-membrane e-dialysis. Izinhlobo ze-fibre ezingenalutho zisetshenziswa kakhulu emtholampilo. Amanye ama-hemodialyzer aklanyelwe ukusetshenziswa kabusha, anokwakhiwa okukhethekile nezinto ezingamelana nokuhlanzwa okuningi kanye nokuhlanza. Okwamanje, ama-dialyzer alahlwayo kumele alahlwe ngemva kokusetshenziswa futhi awakwazi ukusetshenziswa kabusha. Kodwa-ke, kube nempikiswano nokudideka mayelana nokuthi ama-dialyzer kufanele asetshenziswe kabusha yini. Sizohlola lo mbuzo futhi sinikeze incazelo ngezansi.
Izinzuzo kanye nokungalungi kokusebenzisa kabusha ama-dialyzer
(1) Susa isifo sokusetshenziswa kokuqala.
Nakuba kunezinto eziningi ezibangela isifo sokusetshenziswa kokuqala, njengesibulala-magciwane se-ethylene oxide, izinto ezikulwelwesi, ama-cytokine akhiqizwa ukuthintana kwegazi kwelwelwesi lwe-dialysis, njll., kungakhathaliseki ukuthi yiziphi izimbangela, amathuba okuba kwenzeke azoncipha ngenxa yokusetshenziswa okuphindaphindiwe kwe-dialyzer.
(2) Thuthukisa ukuhambisana kwe-dialyzer futhi unciphise ukusebenza kwesistimu yomzimba.
Ngemva kokusebenzisa i-dialyzer, ungqimba lwefilimu yamaprotheni lunamathiselwa ebusweni bangaphakathi be-membrane, okunganciphisa ukusabela kwefilimu yegazi okubangelwa yi-dialysis elandelayo, futhi kunciphise ukusebenza kwe-complement, i-neutrophil degranulation, ukusebenza kwe-lymphocyte, ukukhiqizwa kwe-microglobulin, kanye nokukhululwa kwe-cytokine.
(3) Ithonya lesilinganiso sokususwa kwempahla.
Izinga lokuhlanzwa kwe-creatinine ne-urea alinciphi. Ama-dialyzer okusetshenziswa kabusha ahlanzwe nge-formalin kanye ne-sodium hypochlorite engeziwe angaqinisekisa ukuthi amazinga okuhlanzwa kwezinto eziphakathi nezinkulu zama-molecule (i-Vital12 kanye ne-inulin) ahlala engashintshi.
(4) Nciphisa izindleko ze-hemodialysis.
Akungabazeki ukuthi ukusetshenziswa kabusha kwe-dialyzer kunganciphisa izindleko zokunakekelwa kwempilo kweziguli ezinenkinga yezinso futhi kuhlinzeke ukufinyelela kuma-hemodialyzer angcono kodwa abiza kakhulu.
Ngesikhathi esifanayo, ukushiyeka kokusetshenziswa kabusha kwe-dialyzer nakho kusobala.
(1) Ukusabela okubi kuma-disinfectants
Ukubulala amagciwane kwe-Peracetic acid kuzobangela ukubola kanye nokubola kwe-dialysis membrane, futhi kususe namaprotheni agcinwe ku-membrane ngenxa yokusetshenziswa okuphindaphindiwe, okwandisa amathuba okusebenza kwe-complement. Ukubulala amagciwane kwe-formalin kungabangela ukungezwani komzimba kwe-Anti-N-antibody kanye nesikhumba ezigulini.
(2) Ukwandisa amathuba okungcoliswa kwamagciwane kanye ne-endotoxin kwe-dialyzer futhi kwandise ingozi yokutheleleka okuthelelanayo
(3) Ukusebenza kwe-dialyzer kuyathonywa.
Ngemva kokuba i-dialyzer isetshenziswe izikhathi eziningana, ngenxa yamaprotheni namahlule egazi avimba ama-fiber bundles, indawo esebenzayo iyancishiswa, futhi izinga lokususwa kanye nezinga lokuhluza igazi kuzoncipha kancane kancane. Indlela evamile yokukala ivolumu ye-fiber bundle ye-dialyzer ukubala ivolumu iyonke yawo wonke ama-fiber bundle lumens ku-dialyzer. Uma isilinganiso somthamo ophelele ku-dialyzer entsha singaphansi kuka-80%, i-dialyzer ayikwazi ukusetshenziswa.
(4) Ukwandisa amathuba okuba iziguli kanye nabasebenzi bezokwelapha bavezwe yizinto ezisetshenziswa ngamakhemikhali.
Ngokusekelwe ekuhlaziyweni okungenhla, ukuhlanza nokubulala amagciwane kungalungisa ukushiyeka kokusebenzisa kabusha ama-dialyzer ngezinga elithile. I-dialyzer ingasetshenziswa kabusha kuphela ngemva kwezinqubo zokuhlanza nokubulala amagciwane eziqinile kanye nokuhlolwa okudlule ukuqinisekisa ukuthi akukho ukuqhekeka noma ukuvaleka kwe-membrane ngaphakathi. Ngokungafani nokucubungula ngesandla kwendabuko, ukusetshenziswa kwemishini yokulungisa kabusha i-dialyzer okuzenzakalelayo kungenisa izinqubo ezijwayelekile ekucubungulweni kabusha kwe-dialyzer ukunciphisa amaphutha ekusebenzeni ngesandla. Umshini ungageza ngokuzenzakalelayo, ubulale amagciwane, uhlole, futhi uchithe, ngokwezinqubo nemingcele yokubeka, ukuthuthukisa umphumela wokwelashwa nge-dialysis, ngenkathi kuqinisekiswa ukuphepha kwesiguli kanye nokuhlanzeka.
I-W-F168-B
Umshini wokucubungula kabusha i-dialyzer kaChengdu Wesley uwumshini wokuqala wokucubungula kabusha i-dialyzer ozenzakalelayo emhlabeni ukuze isibhedlela sihlanze, sihlanze, sivivinye, futhi sisebenzise i-dialyzer ephinde isetshenziswe ekwelapheni i-hemodialysis, enesitifiketi se-CE, ephephile futhi ezinzile. I-W-F168-B ene-workstation ephindwe kabili ingafeza ukucubungula kabusha cishe ngemizuzu eyi-12.
Izinyathelo zokuphepha zokusebenzisa kabusha i-dialyzer
Ama-dialyzer angasetshenziswa kabusha kuphela esigulini esifanayo, kodwa izimo ezilandelayo azivunyelwe.
1. Ama-dialyzer asetshenziswa yiziguli ezinezimpawu zegciwane le-hepatitis B ezinhle awakwazi ukusetshenziswa kabusha; ama-dialyzer asetshenziswa yiziguli ezinezimpawu zegciwane le-hepatitis C ezinhle kufanele ahlukaniswe nalawo ezinye iziguli uma esetshenziswa kabusha.
2. Ama-dialyzer asetshenziswa yiziguli ezine-HIV noma i-AIDS awakwazi ukusetshenziswa kabusha
3. Ama-dialyzer asetshenziswa yiziguli ezinezifo ezithathelwanayo ezithwalwa igazi awakwazi ukusetshenziswa kabusha
4. Ama-dialyzer asetshenziswa yiziguli ezine-allergy kuma-disinfectants asetshenziswa ekucubunguleni kabusha awakwazi ukusetshenziswa kabusha
Kukhona futhi nezidingo eziqinile zekhwalithi yamanzi okucubungula kabusha i-hemodialyzer.
Izinga lamagciwane alikwazi ukudlula u-200 CFU/ml kuyilapho umkhawulo wokungenelela ungu-50 CFU/ml; izinga le-Endotoxin alikwazi ukudlula u-2 EU/ml. Ukuhlolwa kokuqala kwe-endotoxin namagciwane emanzini kufanele kube kanye ngesonto. Ngemva kokuba imiphumela yokuhlolwa emibili elandelanayo ihlangabezane nezidingo, ukuhlolwa kwamagciwane kufanele kube kanye ngenyanga, kanti ukuhlolwa kwe-endotoxin kufanele kube okungenani kanye njalo ezinyangeni ezintathu.
(Umshini wamanzi kaChengdu Weslsy we-RO ohlangabezana nezindinganiso zamanzi e-US AAMI/ASAIO dialysis ungasetshenziswa ekucubungulweni kabusha kwe-dialyzer)
Nakuba imakethe yokusetshenziswa kwama-dialyzer aphinde asetshenziswe ibilokhu yehla unyaka nonyaka emhlabeni jikelele, isadingeka kwamanye amazwe nasezifundeni ngomqondo wayo wezomnotho.
Isikhathi sokuthunyelwe: Agasti-16-2024
